Certara Simcyp PBPK Simulator
The industry's most sophisticated platform for physiologically based pharmacokinetic (PBPK) modeling and simulation.
Overview
The Certara Simcyp PBPK Simulator is a leading platform for mechanistic modeling of drug pharmacokinetics. It is widely used in the pharmaceutical industry to predict drug behavior in virtual populations, which helps in optimizing clinical trial design, assessing drug-drug interactions, and supporting regulatory submissions. The platform integrates in vitro data to predict in vivo outcomes.
✨ Key Features
- Physiologically based pharmacokinetic (PBPK) modeling
- Virtual populations (healthy, pediatric, geriatric, disease states)
- Drug-drug interaction (DDI) prediction
- First-in-human (FIH) dose prediction
- Virtual bioequivalence assessment
- Extensive compound and population libraries
- Regulatory acceptance
🎯 Key Differentiators
- Strong focus on population-based modeling and simulation
- Extensive, well-documented compound and population libraries
- Widespread regulatory acceptance and use in drug labels
- Collaborative consortium model for continuous development
Unique Value: Enables the replacement, reduction, and refinement of clinical trials through validated PBPK modeling, leading to more efficient and ethical drug development.
🎯 Use Cases (4)
✅ Best For
- Used in over 250 drug labels for regulatory submissions to the FDA and other agencies.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- Not designed for de novo drug design or initial hit screening.
🏆 Alternatives
Known for its extensive population databases and strong consortium-driven scientific development.
💻 Platforms
✅ Offline Mode Available
🔌 Integrations
🛟 Support Options
- ✓ Email Support
- ✓ Phone Support
- ✓ Dedicated Support (Standard tier)
🔒 Compliance & Security
💰 Pricing
✓ 14-day free trial
Free tier: NA
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