Clue
A platform for connecting genes, drugs, and disease.
Overview
Clue.io, developed by the Broad Institute, is a cloud-based platform that provides access to a massive dataset of gene expression profiles from cells treated with various small molecules and genetic perturbations. While primarily a research tool, it is highly valuable for biomarker discovery and hypothesis generation in the early stages of drug development. Researchers can use Clue to explore the effects of compounds on gene expression, identify potential biomarkers of drug response, and understand the mechanisms of action of drugs.
✨ Key Features
- Massive dataset of gene expression profiles (L1000)
- Tools for querying and analyzing the data
- Connectivity mapping to link genes, drugs, and diseases
- Web-based interface for easy access and exploration
- API for programmatic access
🎯 Key Differentiators
- Unprecedented scale of the L1000 dataset
- Focus on connectivity mapping
- Open and accessible to the research community
Unique Value: Provides a massive and unique dataset that enables researchers to make novel connections between genes, drugs, and diseases, driving new avenues for biomarker discovery.
🎯 Use Cases (4)
✅ Best For
- Widely used by the academic and pharmaceutical research communities.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- Managing and analyzing clinical trial biomarker data.
🏆 Alternatives
Offers a more data-driven and unbiased approach to hypothesis generation compared to knowledge-based pathway analysis tools.
💻 Platforms
🔌 Integrations
🛟 Support Options
- ✓ Email Support
- ✓ Dedicated Support (N/A tier)
💰 Pricing
Free tier: Free for academic and non-profit research.
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